It depends on the context
If I’m just looking for a confirmation that my message was received, and the plans need to additional modification, a thumbs up is sufficient.
If I ask something like “Wanna meet up at the bar after work today?” And get a thumbs up, that’s sufficient. We know where we’re going and when, no more discussion really needed.
If I ask “you free to grab a beer this weekend?” and I get a thumbs up, that’s bullshit. When are you free to grab said beer? Where are we going for it? We have details that need to be hammered out.
If you intend to continue living in America for now, DO NOT LEAVE THE COUNTRY if it can be at all avoided. Not into Canada, not Mexico, not to any other country, not by land, sea, or air. If you can, stay at least 100 miles away from any border.
Don’t count on your visa, green card, or any other documentation and paperwork you may have being sufficient to allow you back into the country. Honestly, I don’t think we’re far from you being potentially barred from returning even if you’re a naturalized citizen.
If you must leave the country for any reason, do so with the knowledge that you may not be allowed to return. Bring your important documents, extra cash, clothes, etc. make arrangements for your pets, figure out what your next move will be if you get to the US border and are denied entry, where will you go, who will you stay with, etc.